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MCF2

MCF2 (or DBL) is a member of a large family of GDP-GTP exchange factors (ARHGEFs) that modulate the activity of small GTPases of the Rho family (RHOs).

MCF2-like guanine nucleotide exchange factors (GEFs), such as ARHGEFs, catalyze the exchange of bound GDP for GTP on Rho-related proteins.