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botryoid rhabdomyosarcoma

Friday 26 October 2007

Digital case

- Case 211 (HPC:211) : Botryoid embryonal rhabdomyosarcoma
- Case 250 : Botryoid embryonal rhabdomyosarcoma of the nasopharynx

Definition: Botryoid rhabdomyosarcoma is a subset of embryonal rhabdomyosarcoma. It accounts for 6% of all cases of rhabdomyosarcomas.

Botryoid rhabdomyosarcoma arises under the mucosal surfaces of body orifices; therefore, it is most commonly observed in areas such as the vagina, bladder, and nares.

Botryoid rhabdomyosarcoma is distinguished by the formation of polypoid and grapelike tumor masses. On histologic study, botryoid rhabdomyosarcoma demonstrates malignant cells in an abundant myxoid stroma.

Differential diagnosis

- botryoid tumors

Case studies

- HP.14683

See also

- rhabdomyosarcomas

  • embryonal rhabdomyosarcoma


- Riedlinger WF, Kozakewich HP, Vargas SO. Myogenic markers in the evaluation of embryonal botryoid rhabdomyosarcoma of the female genital tract. Pediatr Dev Pathol. 2005 Jul-Aug;8(4):427-34. PMID: 16220232