Home > A. Molecular pathology > CREB1-EWSR1
CREB1-EWSR1
Wednesday 29 August 2007
EWSR1/CREB1; EWSR1-CREB1
Fusion gene fornation by translocation
CREB1 at 2q32-q34 and EWSR1 at 22q12
Tumors
clear cell sarcoma ( soft parts melanoma ) (17000668)
angiomatoid fibrous histiocytoma (AFH) (17724745)
Ewing sarcoma / small blue round cell tumor (20598147)
See also
CREBSs
ATF1-FUS
ATF1-EWSR1
Open references
Small blue round cell tumor of the interosseous membrane bearing a t(2;22)(q34;q12)/EWS-CREB1 translocation: a case report. Pacheco M, Horsman DE, Hayes MM, Clarkson PW, Huwait H, Nielsen TO. Mol Cytogenet. 2010 Jul 2;3:12. doi : 10.1186/1755-8166-3-12 PMID: 20598147 Free
Paywall References
Antonescu CR, Nafa K, Segal NH, Dal Cin P, Ladanyi M. EWS-CREB1: a recurrent variant fusion in clear cell sarcoma—association with gastrointestinal location and absence of melanocytic differentiation. Clin Cancer Res. 2006 Sep 15;12(18):5356-62. PMID: 17000668
Antonescu CR, Dal Cin P, Nafa K, Teot LA, Surti U, Fletcher CD, Ladanyi M. EWSR1-CREB1 is the predominant gene fusion in angiomatoid fibrous histiocytoma. Genes Chromosomes Cancer. 2007 Aug 20; PMID: 17724745
