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loss-of-function genetic disease
Saturday 28 July 2007
Loss-of-function genetic diseases are caused by the impairment of one protein by loss-of-function mutations.
See also
genetic diseases
- gain-of-function genetic diseases
gene mutations
- loss-of-function mutations
- gain-of-function mutations
References
Segalat L. Loss-of-function genetic diseases and the concept of pharmaceutical targets. Orphanet J Rare Dis. 2007 Jul 2;2(1):30 PMID: 17605800
