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midfacial necrotizing lesions
Thursday 12 July 2007
The necrotizing lesions of the midfacial mucous membranes can be
(1) localized or part of a systemic illness
(2) neoplastic or non-neoplastic
(3) caused by a specific agent or organism or be seemingly idiopathic;
(4) self-limited or progressively destructive in varying degrees of severity;
(5) characterized by a granulomatous or nonspecific tissue reaction with or without vasculitis;
(6) impossible to classify without clinicopathologic correlation.
Etiology (Examples)
sarcoidosis
Wegener granulomatosis
lymphomatoid granulomatosis
Differential diagnosis
lethal midline granuloma
References
Batsakis JG, Luna MA. Midfacial necrotizing lesions. Semin Diagn Pathol. 1987 May;4(2):90-116. PMID: 3313603
