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microvesicular steatosis

Thursday 24 May 2007

Digital slides

- Case A: NCK2-25, NCK2-26, NCK2-27: Niemann-Pick disease type B (NPB)

Etiology

- acute fatty liver of pregnancy
- Reye syndrome
- drugs

  • salicylate toxicity
  • sodium valproate toxicity
  • tetracycline toxicity
  • 2-arylpropionic acids (e.g. ketoprofen)
  • amineptine
  • MDMA (ecstasy)
  • didanosine
  • fialuridine
  • stavudine

- acute iron toxicity
- aflatoxins
- jamaican vomiting disease
- multiple hornet stings
- alcoholic foamy degeneration

- genetic metabolic diseases

  • inherited urea cycle diseases
  • inherited diseases of fatty acid metabolism
  • oxydative phosphorylation diseases (mitochondrial cytopathies)
  • Wolman disease
  • cholesterol ester storage disease
  • Niemann-Pick disease type B

- hepatitis D infection (Labrea fever)
- Bacillus cereus toxins
- Navajo neuropathy
- Pearson syndrome

Types

- centrilobular microvesicular steatosis

See also

- Steatosis

- non-alcoholic steatohepatitis (NASH)

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