HCV

Pathology

 non-A non-B hepatitis
 type II cryoglobulinemia

 HCV-associated B-cell lymphomas

• lymphoplasmacytoid lymphoma
• immunocytoma-lymphoma
• marginal zone lymphoma
• splenic lymphomas
  • diffuse primary hepatosplenic large cell lymphoma
  • splenic lymphoma with vilous lymphocytes
  • splenic diffuse large B-cell lymphoma (DLBCL) (16112004)
  • splenic marginal zone lymphoma (SMZL)
  • hepatosplenic T-cell and natural killer cell lymphoma

Videos

 Hepatitis C virus

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References

 De Clercq E. The design of drugs for HIV and HCV. Nat Rev Drug Discov. 2007 Dec;6(12):1001-18. PMID: 18049474

 Manns MP, Foster GR, Rockstroh JK, Zeuzem S, Zoulim F, Houghton M. The way forward in HCV treatment—finding the right path. Nat Rev Drug Discov. 2007 Dec;6(12):991-1000. PMID: 18049473

 Dubuisson J, Penin F, Moradpour D. Interaction of hepatitis C virus proteins with host cell membranes and lipids. Trends Cell Biol. 2002 Nov;12(11):517-23. PMID: 12446113

 Moradpour D, Brass V, Gosert R, Wolk B, Blum HE. Hepatitis C: molecular virology and antiviral targets. Trends Mol Med. 2002 Oct;8(10):476-82. PMID: 12383770