EDN1
MIM.131240 6p24-p23
Endothelin-1 (ET-1), a vasoactive and mitogenic peptide mainly produced by vascular endothelial cells, may be involved in the progression of several human tumors.
References
Functional endothelin ET B receptors are selectively expressed in human oligodendrogliomas. Anguelova E, Beuvon F, Leonard N, Chaverot N, Varlet P, Couraud PO, Daumas-Duport C, Cazaubon S. Brain Res Mol Brain Res. 2005 Jun 13;137(1-2):77-88. PMID: #15950764#
Pare G, Serre D, Brisson D, Anand SS, Montpetit A, Tremblay G, Engert JC, Hudson TJ, Gaudet D. Genetic analysis of 103 candidate genes for coronary artery disease and associated phenotypes in a founder population reveals a new association between endothelin-1 and high-density lipoprotein cholesterol. Am J Hum Genet. 2007 Apr;80(4):673-82. PMID: #17357073#