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BRCA2-associated mammary carcinoma

Tuesday 9 January 2007

BRCA2-associated breast cancers are predominantly high-grade invasive ductal carcinomas of no special type and they demonstrate a luminal phenotype despite their high histologic grade. (17197928)

See also

- BRCA2
- BRCA1

  • BRCA2-associated mammary carcinoma

References

- Prediction of BRCA2-association in hereditary breast carcinomas using array-CGH. Joosse SA, Brandwijk KI, Devilee P, Wesseling J, Hogervorst FB, Verhoef S, Nederlof PM. Breast Cancer Res Treat. 2010 Jul 8. PMID: 20614180

- Fackenthal JD, Olopade OI. Breast cancer risk associated with BRCA1 and BRCA2 in diverse populations. Nat Rev Cancer. 2007 Dec;7(12):937-48. PMID: 18034184

- Bane AL, Beck JC, Bleiweiss I, Buys SS, Catalano E, Daly MB, Giles G, Godwin AK, Hibshoosh H, Hopper JL, John EM, Layfield L, Longacre T, Miron A, Senie R, Southey MC, West DW, Whittemore AS, Wu H, Andrulis IL, O’malley FP; for the Breast Cancer Family Registry. BRCA2 Mutation-associated Breast Cancers Exhibit a Distinguishing Phenotype Based on Morphology and Molecular Profiles From Tissue Microarrays. Am J Surg Pathol. 2007 Jan;31(1):121-128. PMID: 17197928