Home > E. Pathology by systems > Digestive system > Liver and pancreatobiliary system > Pancreas > pancreatic hepatoid carcinoma
pancreatic hepatoid carcinoma
Tuesday 9 January 2007
Hepatoid adenocarcinomas are tumors that display, at least focally, cytologic and/or architectural features of hepatocellular carcinoma. They have been described in several organs, most notably in the stomach and ovary and in the pancreas.
Synopsis
monotonous, small-to-medium sized tumor cells with round nuclei and finely granular chromatin
more atypical tumor cells displaying larger nuclei with coarse clumped chromatin, prominent nucleoli, and moderate amounts of foamy cytoplasm
poorly differentiated pancreatic endocrine carcinoma associated with well-defined islands of larger tumor cells growing in a perisinusoidal pattern
Differential diagnosis
pancreatic tumors composed of large eosinophilic cells
References
Hameed O, Xu H, Saddeghi S, Maluf H. Hepatoid carcinoma of the pancreas: a case report and literature review of a heterogeneous group of tumors. Am J Surg Pathol. 2007 Jan;31(1):146-52. PMID: 17197931
