Human pathology

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neonatal urate deposits

Image Gallery

Renal urate deposits in a neonate Renal urate deposits in a neonate
Renal uric acid deposition in neonate

Synopsis

- yellow striations along the collecting ducts in the inner renal medulla
- amorphous eosinophilic residues

Associations

- fetal hypoxia and neonatal hypoxia

  • acceleration of anaerobic metabolism
  • cardiac malformations (congenital heart disease) (685909)
    • Taussig-Bing anomaly and interruption of the aortic arch (7997431)

- hypoxanthine guanine phosphoribosyl transferase (HGPRT) deficiency (Lesch-Nyhan syndrome) (6639135)

See also

- neonatal renal failure (10750078)
- fetal hyperuricemia abd neonatal hyperuricemia

  • uric acid overproduction by cellular destruction
    • secondary polycythemia
  • uric acid excretion by the kidney
  • acceleration of anaerobic metabolism

See also

- hyperuricemia
- urate deposits
- uric acid nephropathy

References

- Potter, Pathology of the Fetus and infant p.889 ISBN 0801678706