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TLE1

HP:15471

MIM.600189 9q21.32 HGNC:11837

TLE1 encodes a transcriptional corepressor that is overexpressed in synovial sarcomas.

Gene and tissue microarray studies have identified TLE1 as an excellent bio-marker for distinguishing the synovial sarcoma from other soft tissue malignancies.

References

Prospective Evaluation of TLE1 as a Diagnostic Immunohistochemical Marker in Synovial Sarcoma. Jagdis A, Rubin BP, Tubbs RR, Pacheco M, Nielsen TO. Am J Surg Pathol. 2009 Oct 3. PMID: 19809272

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