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chromosomal aberrations

chromosomal rearrangements, chromosome aberrations

 

Types

-  chromosomal translocations
-  chromosomal deletions

Classification

-  recurrent chromosomal rearrangements
-  nonrecurrent chromosomal rearrangements

Features

-  chromosoaml aberrations in cancer

References

-  Albertson DG, Collins C, McCormick F, Gray JW. Chromosome aberrations in solid tumors. Nat Genet. 2003 Aug;34(4):369-76. PMID: #12923544#

-  Mitelman F, Johansson B, Mertens F. Fusion genes and rearranged genes as a linear function of chromosome aberrations in cancer. Nat Genet. 2004 Apr;36(4):331-4. PMID: #15054488#

-  Stankiewicz P, Lupski JR. Genome architecture, rearrangements and genomic disorders. Trends Genet. 2002 Feb;18(2):74-82. PMID: #11818139#



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