The terms 'chemoprotection' or 'radioprotection' refer to the protection of normal cells from the toxicity of cancer chemotherapeutic agents or radiotherapy.

As the concentration of oxygen and thiols in the vicinity of the DNA has a marked effect on the cellular radiosensitivity, pharmacological modulation of oxygenation in the normal cells has been used as an approach to protect normal cells from ionizing radiation.

Example

 amifostine