transcription factors
Classification
| HOXs | ETSs | SOXs | FOXCs | TBXs | PAXs | TBOXs | PHOXs | PPARs | ZNFs | POUs |
transcription factors in cancer
transcription factors in development anomalies (developmental disorders)
Pathology (developmental disorders)
TBX5: Mutations in TBX5, a T-box-containing transcription factor, cause cardiac and limb malformations in individuals with Holt-Oram syndrome (HOS).
Pathology (by molecular groups)
Pathology of SOXs
Pathology of FOXCs
Pathology of TBXs (T-box proteins)
Pathology of PAXs
Features
lineage-specific transcription factors
References
Darnell JE Jr. Transcription factors as targets for cancer therapy. Nat Rev Cancer. 2002 Oct;2(10):740-9. PMID: #12360277#
Hart SM. Modulation of nuclear receptor dependent transcription. Biol Res. 2002;35(2):295-303. PMID: #12415747#
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