Loci modifying the age of onset (#12900792#)
4p16
6p21-23
6q24-26
References
Li SH, Li XJ. Huntingtin-protein interactions and the pathogenesis of Huntington's disease. Trends Genet. 2004 Mar;20(3):146-54. PMID: #15036808#
Li JY, Plomann M, Brundin P. Huntington's disease: a synaptopathy? Trends Mol Med. 2003 Oct;9(10):414-20. PMID: #14557053#
Sugars KL, Rubinsztein DC. Transcriptional abnormalities in Huntington disease. Trends Genet. 2003 May;19(5):233-8. PMID: #12711212#
Rubinsztein DC. Lessons from animal models of Huntington's disease. Trends Genet. 2002 Apr;18(4):202-9. PMID: #11932021#
Nasir J, Goldberg YP, Hayden MR. Huntington disease: new insights into the relationship between CAG expansion and disease. Hum Mol Genet. 1996;5 Spec No:1431-5. PMID: #8875248#
Tobin AJ, Signer ER. Huntington's disease: the challenge for cell biologists. Trends Cell Biol. 2000 Dec;10(12):531-6. PMID: #11121745#