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sarcoidosis

 
Sarcoidosis is a granulomatous disorder of unknown etiology, associated with an accumulation of CD4+ T cells and a TH1 immune response.

Localization

-  pulmonary sarcoidosis
-  nodal sarcoidosis
-  hepatic sarcoidosis
-  salivary sarcoidosis

Types

-  early-onset sarcoidosis
-  induced by recombinant interferon-alpha (IFN-alpha) (IFN-associated sarcoidosis) (#15958865#)

Susceptibility loci

-  truncating splice site mutation in BTNL2 gene (#15735647#)
-  CARD15 mutations in early-onset sarcoidosis
-  HLA-DRB1 locus (#12934202#)



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