ossification of the posterior longitudinal ligament of the spine
OPLL
Ossification of the posterior longitudinal ligament (OPLL) of the spine is a subset of "bone-forming" diseases, characterized by ectopic ossification in the spinal ligaments. OPLL is a common disorder among elderly populations in eastern Asia and is the leading cause of spinal myelopathy in Japan.
Susceptibility loci
COL6A1 (21q22.3) (#12958705#)
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