Synopsis

 cystic lesion

• unifocal
• multifocal

 Size: microscopic size to 2 cm in diameter
 thin-walled, semitranslucent, filled with clear or yellowish fluid or gelatinous contents
 cysts were with a single layer of flattened or cuboid mesothelial cells (CK+, calretinin+)
 diffuse squamous cell metaplasia
 cells focally forming small papillae
 vacuolated cells
 no mucus

Immunohistochemistry

 CK +
 calretin +

Differential diagnosis

 splenic lymphangiomas (#9060604#)
 splenic lymphangiomatosis (#9060604#)

See also

 mesothelial cysts
 diaphragmatic mesothelial cyst
 hepatic mesothelial cyst
 splenic mesothelial cyst

References

 Arber DA, Strickler JG, Weiss LM. Splenic mesothelial cysts mimicking lymphagiomas. Am J Surg Pathol. 1997 Mar;21(3):334-8. PMID: #9060604#