Subtypes

 portal lesions

• chronic hepatitis without activity

 peripotal lesions

• piecemeal necrosis
• periportal fibrosis

 lobular lesions

• chronic lobular hepatitis
• hepatocytic necrosis
• swollen hepatocytes
• giant multinucleated hepatocytes

Lesional syndromes

 chronic active hepatitis

Etiology

 viral chronic hepatitis
 autoimmune chronic hepatitis
 drug-induced chronic hepatitis
 Wilson disease
 alpha1-antitrypsin deficiency
 chronic alcoholic abuse

Synopsis

 mononuclear portal inflammation
 focal hepatocytic necrosis

Differential diagnosis

 resolving acute hepatitis
 nonspecific reactive hepatitis
 hepatic lymphomas

References

 Batts KP, Ludwig J. Chronic hepatitis. An update on terminology and reporting. Am J Surg Pathol. 1995 Dec;19(12):1409-17. PMID: #7503362#