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8q22
Pathology
t(8;21)(q22;q22)
- acute myeloid leukemia (5-12%) (one of the most common structural aberration in AML)
- translocation t(8;21)(q22;q22) involves genes CBFA (AML1) (at 21q22) and RUNX1 (ETO) (at 8q22) (CBFA/RUNX1 fusion gene or AML1/ETO)
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