Lesions

 loss of interstitial cells of Cajal

• paraneoplastic dysmotility

 structural anomalies

Pathology

 paraneoplastic dysmotility
 Hirschsprung disease
 hypertrophic pyloric stenosis
 chronic intestinal pseudo-obstruction
 slow transit constipation

References

 Jain D, Moussa K, Tandon M, Culpepper-Morgan J, Proctor DD. Role of interstitial cells of Cajal in motility disorders of the bowel. Am J Gastroenterol. 2003 Mar;98(3):618-24. PMID: #12650797#

 Pardi DS, Miller SM, Miller DL, Burgart LJ, Szurszewski JH, Lennon VA, Farrugia G. Paraneoplastic dysmotility: loss of interstitial cells of Cajal. Am J Gastroenterol. 2002 Jul;97(7):1828-33. PMID: #12135044#