Human pathology

Home page > G. Tumoral pathology > small lymphocytic lymphoma

small lymphocytic lymphoma

Synopis

- indolent disease
- leukemic involvement by lymphoid cells, including prolymphocytes and/or paraimmunoblasts
- splenomegaly

Immunochemistry

- Pan-B+;
- CD5+
- CD23+
- CD10-
- sIgM+ faint

Putative cell of origin:

- CD5+ virgin B-cell with germline IgV genes

Cytogenetics

- del(6)(q21-23) (20-30% of the cases)

P.S.


- AGCOH