Members
HOX11 (MIM.186770) - translocated at TCRD at 14q11 (MIM.186810) or TCRB at 7q35 (MIM.186930) by t(10;14)(q24;q11) or t(7;10)(q35;q24) in 7% of childhood T-cell acute leukemia
Hox A cluster at 7p15-p14.2
HOXA1 (MIM.142955)
HOXA2 (MIM.604685)
HOXA3 (MIM.142954)
HOXA4 (MIM.142953)
HOXA5 (MIM.142952)
HOXA6 (MIM.142951)
HOXA7 (MIM.142950)
HOXA9 (MIM.142956) - fused in the HOXA9/MSI2 Fusion Gene by t(7;17)(p15;q23) in chronic myeloid leukemia
HOXA10 (MIM.142957)
HOXA11 (MIM.142958)
HOXA13 (MIM.142959)
Hox B cluster at 17q21-q22
HOXB1 (MIM.142968)
HOXB2 (MIM.142967)
HOXB3 (MIM.142966)
HOXB4 (MIM.142965)
HOXB6 (MIM.142961)
HOXB7 (MIM.142962)
HOXB8 (MIM.142963)
HOXB9 (MIM.142964)
HOXB13 (MIM.604607)
Hox C cluster at 12q13
HOXC4 (MIM.142974)
HOXC6 (MIM.142972)
HOXC8 (MIM.142970)
HOXC10 (MIM.605560)
HOXC11 (MIM.605559)
HOXC13 (MIM.142976) - fused in the HOXC13/NUP98 (MIM.601021) by t(11;12)(p15;q13) in acute myeloid leukemia
HOXC9 (MIM.142971)
Hox D cluster at 2q31-q32
HOXD1 (MIM.142987)
HOXD3 (MIM.142980)
HOXD4 (MIM.142981)
HOXD8 (MIM.142985)
HOXD9 (MIM.142982)
HOXD10 (MIM.142984)
HOXD11 (MIM.142986) - fused in the HOXD11/NUP98 fusion gene by t(2;11)(q31;p15) in acute myeloid leukemia
HOXD12 (MIM.142988)
HOXD13 (MIM.142989) - fused in the HOXD13/NUP98 fusion gene in acute myeloid leukemia - mutations in synpolydactyly (MIM.186000) with or without foot anomaly, brachydactyly types D (MIM.113200) and E (MIM.113300) (#12649808#)
References
Abate-Shen C. Deregulated homeobox gene expression in cancer: cause or consequence? Nat Rev Cancer. 2002 Oct;2(10):777-85. PMID: #12360280#