Phosphorylation events are key to most nuclear and cytoplasmic processes. Cellular protein kinases and phosphatases are involved in the regulation of differentiation, cell division, transcription, and DNA repair. Phosphorylation and dephosphorylation can either activate or inactivate other proteins.
See also
Kinases
References
Rothman DM, Shults MD, Imperiali B. Chemical approaches for investigating phosphorylation in signal transduction networks. Trends Cell Biol. 2005 Sep;15(9):502-10. PMID: #16084095#