POLB
MIM.174760 8p11.2
DNA polymerase beta
In eukaryotic cells, DNA polymerase beta (POLB) performs base excision repair (BER) required for DNA maintenance, replication, recombination, and drug resistance.
Two important enzymatic steps in mammalian BER are contributed by POLB: DNA resynthesis of the repair patch and lyase removal of the 5-prime-deoxyribose phosphate.
base excision repair (BER)
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