cardiac sarcomere
Components
thick filament
- cardiac myosin binding protein C
- regulatory and essential light chains
- beta myosin heavy chain
thin filament
- troponin-I
- troponin-T
- tropomyosin
- actin
Pathology (sarcomeropathies)
Mutations in genes encoding each of the proteins can cause hyertrophic cardiomyopathy.
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