endometrial stromal sarcoma
Immunochemistry
SMM-HC+ (smooth muscle myosin heavy chain)
CD10+
calponin+
Cytogenetics
t(3;6)(q29;p21.1) (#14580778#)
t(7;17)(p15;q21) (JAZF1-JJAZ1 fusion gene)
t(10;17)(q22;p13) (#14529693#)
t(X;17)(p11:q23)
Molecular biology
fusion genes between JAZF1 at 7p15 and JJAZ1 at 17q21 by t(7;17)(p15;q21) (#12850374#, #11371647#)
Differential diagnosis
endometrial stromal tumors
- benign stromal nodule
- undifferentiated endometrial sarcoma
uterine smooth muscle tumors
- cellular uterine leiomyoma
- uterine leiomosarcoma
Forum de l'article
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