Constrictive bronchiolitis designates inflammation and fibrosis occurring predominantly in the walls and contiguous tissues of membranous and respiratory bronchioles, with resultant narrowing of their lumens.

Synopsis

 concentric bronchiolar fibrosis

Types

 active constrictive bronchiolitis
 inactive constrictive bronchiolitis

Etiology

 organ allograft

• lung allograft
• heart-lung allograft
• bone marrow allograft

 healed pulmonary infections

• respiratory syncitial virus (VRS)
• cytomegalovirus
• adenovirus
• influenza virus
• parainfluenza virus
• varicella
• mycoplasma

 fumes

• nitrogen oxide

 toxins (inhaled or ingested)

• Sauropus androgynous

 drugs

• penicillamine
• lomustine

 dysimmunity

• rheumatoid arthritis
• pemphigus vulgaris
• inflammatory bowel diseases (IBDs)

 drugs

 allografts

• bone marrow allograft
• pulmonary allograft rejection

 diffuse idiopathic pulmonary neuroendocrine cell hyperplasia
 asthma
 extrinsic allergic alveolitis
 idiopathic constrictive bronchiolitis

See also

 bronchiolitis

• obliterative bronchiolitis
  • bronchiolitis obliterans syndrome (BOS)

References

 Schlesinger C, Veeraraghavan S, Koss MN. Constructive (obliterative) bronchiolitis. Curr Opin Pulm Med. 1998 Sep;4(5):288-93. PMID: #10813204#

 Schlesinger C, Meyer CA, Veeraraghavan S, Koss MN. Constrictive (obliterative) bronchiolitis: diagnosis, etiology, and a critical review of the literature. Ann Diagn Pathol. 1998 Oct;2(5):321-34. PMID: #9845757#