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armadillo repeat proteins

 

Armadillo-like proteins are characterized by a series of armadillo repeats, first defined in the Drosophila 'armadillo' gene product, that are typically 42 to 45 amino acids in length.

These proteins can be divided into subfamilies based on their number of repeats, their overall sequence similarity, and the dispersion of the repeats throughout their sequences.

Members

CTNNDs CTNND1 CTNND2
PKPs PKP1 PKP2 PKP3 PKP4
ARVCF

-  delta-1-catenin CTNND1 (MIM.601045)
-  delta-2-catenin CTNND2 (MIM.604275)
-  plakophilin-1 PKP1 (MIM.601975)
-  plakophilin-2 PKP2 (MIM.602861)
-  plakophilin-4 PKP4
-  ARVCF (armadillo repeat gene deleted in velocardiofacial syndrome)(MIM.602269)

References

-  Tolwinski NS, Wieschaus E. Rethinking WNT signaling. Trends Genet. 2004 Apr;20(4):177-81. PMID: #15041171#



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