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TSCs

tuberous sclerosis complex genes

 

Members

TSC1 TSC2

References

-  Findlay GM, Harrington LS, Lamb RF. TSC1-2 tumour suppressor and regulation of mTOR signalling: linking cell growth and proliferation? Curr Opin Genet Dev. 2005 Feb;15(1):69-76. PMID: #15661536#

-  Henske EP. The genetic basis of kidney cancer: why is tuberous sclerosis complex often overlooked? Curr Mol Med. 2004 Dec;4(8):825-31. PMID: #15579029#

-  Mak BC, Yeung RS. The tuberous sclerosis complex genes in tumor development. Cancer Invest. 2004;22(4):588-603. PMID: #15565817#

-  Yeung RS. Multiple roles of the tuberous sclerosis complex genes. Genes Chromosomes Cancer. 2003 Dec;38(4):368-75. PMID: #14566857#


TSCs and the PI3K/PTEN/AKT signaling pathway

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