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desmoglein-4

DSG4

 
Desmoglein-4 is the main desmosome cadherin in hair follicle.

Pathology

-  DSG4 is an autoantigen in pemphigus vulgaris (MIM.169610).
-  mutation in the gene encoding desmoglein-4 (DSG4) causes localized autosomal recessive hypotrichosis (LAH) (MIM.607903)


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