Definition: An ischemic stroke is a cerebrovascular accident that results from occlusion of cerebral arteries owing to atherosclerosis and leading to a neurological deficit or death.
References
Gulcher JR, Gretarsdottir S, Helgadottir A, Stefansson K. Genes contributing to risk for common forms of stroke. Trends Mol Med. 2005 May;11(5):217-24. PMID: #15882609#
Zheng Z, Lee JE, Yenari MA. Stroke: molecular mechanisms and potential targets for treatment. Curr Mol Med. 2003 Jun;3(4):361-72. PMID: #12776991#
Lo EH, Dalkara T, Moskowitz MA. Mechanisms, challenges and opportunities in stroke. Nat Rev Neurosci. 2003 May;4(5):399-415. PMID: #12728267#
Tournier-Lasserve E. New players in the genetics of stroke. N Engl J Med. 2002 Nov 21;347(21):1711-2. PMID: #12444190#