Nestin is an intermediate filament protein that is expressed predominantly in stem cells of the central nervous system in the neural tube. Upon terminal neural differentiation, nestin is downregulated and replaced by neurofilaments. Its expression is also related to tooth development and repair of dentine.

See also

 intermediate filaments
 cytoskeleton

References

 Fujita S, Hideshima K, Ikeda T. Nestin expression in odontoblasts and odontogenic ectomesenchymal tissue of odontogenic tumours. J Clin Pathol. 2006 Mar;59(3):240-5. PMID: #16505272#