Genomic instability diseases

 DExH-containing DNA helicases

• XPD
• XPB
• WRN
• BLM

References

 Charames GS, Bapat B. Genomic instability and cancer. Curr Mol Med. 2003 Nov;3(7):589-96. PMID: #14601634#

 Chin K, De Solorzano CO, Knowles D, Jones A, Chou W, Rodriguez EG, Kuo WL, Ljung BM, Chew K, Myambo K, Miranda M, Krig S, Garbe J, Stampfer M, Yaswen P, Gray JW, Lockett SJ. In situ analyses of genome instability in breast cancer. Nat Genet. 2004 Aug 8 PMID: #15300252#

 Charames GS, Bapat B. Genomic instability and cancer. Curr Mol Med. 2003 Nov;3(7):589-96. PMID: #14601634#

 De la Torre C, Pincheira J, Lopez-Saez JF. Human syndromes with genomic instability and multiprotein machines that repair DNA double-strand breaks. Histol Histopathol. 2003 Jan;18(1):225-43. PMID: #12507302#

 Sieber OM, Heinimann K, Tomlinson IP. Genomic instability--the engine of tumorigenesis? Nat Rev Cancer. 2003 Sep;3(9):701-8. PMID: #12951589#

 Rajagopalan H, Nowak MA, Vogelstein B, Lengauer C. The significance of unstable chromosomes in colorectal cancer. Nat Rev Cancer. 2003 Sep;3(9):695-701. PMID: #12951588#

 Feldser DM, Hackett JA, Greider CW. Telomere dysfunction and the initiation of genome instability. Nat Rev Cancer. 2003 Aug;3(8):623-7. PMID: #12894250#

 Matzke MA, Mette MF, Kanno T, Matzke AJ. Does the intrinsic instability of aneuploid genomes have a causal role in cancer? Trends Genet. 2003 May;19(5):253-6. PMID: #12711216#

 Bohr VA: Human premature aging syndromes and genomic instability. Mech Ageing Dev 123:987, 2002.