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CTTNA1

MIM.116805 5q31

 

E-cadherin is a transmembrane glycoprotein responsible for physical connection of epithelial cells through Ca(2+)-binding regions in its extracellular domain.

E-cadherin-mediated cell-cell adhesion is effected by 3 cytoplasmic proteins known as catenins alpha (CTTNAs), beta (CTTNBs), and gamma (junction plakoglobin JUP).


Alpha-catenin and adherens junction - (Rockfeller univeristy)

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