ganglioneuroblastomas

ganglioneuroblastoma

The ganglioneuroblastoma are rare lesions with widespread neuronal differentiation that have been classified as intermediate stages between neuroblastoma and ganglioneuroma.

Types

intermixed ganglioneuroblastoma
nodular ganglioneuroblastoma

Cytogenetics

constitutional t(1;13)(q21;q12) with truncation and inactivation of WASF3 (#7972239#)

CGH

Losses

Gains

2p25-pter (60%)
5p15.1-p15.3 (60%)
7 (60%)
13q22-q31 (60%)
22 (60%)

See also

neuroblastic tumors

neuroblastomas

References

Joshi VV. Peripheral neuroblastic tumors: pathologic classification based on recommendations of international neuroblastoma pathology committee (Modification of shimada classification). Pediatr Dev Pathol. 2000 Mar-Apr;3(2):184-99. PMID: #10679039#