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midline developmental anomalies

midline defects, schisis-association

 

Types (exemples)

-  neural tube defects (NTDs)

-  oral clefts
-  omphalocele
-  esophageal atresia/tracheoesophageal fistula
-  imperforate anus
-  conotruncal heart defects
-  diaphragmatic hernia

Associations

-  Fryns syndrome

References

-  Khoury MJ, Cordero JF, Mulinare J, Opitz JM. Selected midline defect associations: a population study. Pediatrics. 1989 Aug;84(2):266-72. PMID: #2748254#

-  Czeizel A. Schisis-association. Am J Med Genet. 1981;10(1):25-35. PMID: #7294060#



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