CDSN
MIM.602593 6p21.3
corneodesmosin
Corneodesmosin (CDSN) is a rotein of corneodesmosomes. Corneodesmosomes are intercellular structures that are involved in desquamation, the shedding of superficial corneocytes from the skin surface. Corneocytes are anucleated cells derived from keratinocytes during the late stages of terminal differentiation of cornified squamous epithelia such as the epidermis.
germline mutations of CDSN in hypotrichosis simplex of the scalp (MIM.146520)
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