ARC syndrome is the association of arthrogryposis, renal tubular acidosis, and cholestasis.

Synopsis

 arthrogryposis
 renal tubular acidosis with renal Fanconi syndrome

• nephrogenic diabetes insipidus

 cholestasis with jaundice
 ichthyosis
 recurrent febrile illnesses
 diarrhoea
 failed to thrive
 abnormally large platelets
 dysmorphism

References

 Eastham KM, McKiernan PJ, Milford DV, Ramani P, Wyllie J, van't Hoff W, Lynch SA, Morris AA. ARC syndrome: an expanding range of phenotypes. Arch Dis Child. 2001 Nov;85(5):415-20. PMID: #11668108#