intravascular large B-cell lymphoma
Intravascular large B-cell lymphoma (LBCL) is a rare and aggressive subtype of diffuse LBCL characterized by disseminated intravascular proliferation of neoplastic lymphocytes.
Obstruction of blood flow by tumor cells in a variety of organs can cause an array of clinical changes, including alteration of the neural and spinal system and the respiratory system, as well as skin lesions.
References
Seki K, Miyakoshi S, Lee GH, Matsushita H, Mutoh Y, Nakase K, Ida M, Taniguchi H. Prostatic Acid Phosphatase Is a Possible Tumor Marker for Intravascular Large B-Cell Lymphoma. Am J Surg Pathol. 2004 Oct;28(10):1384-1388. PMID: 15371956