SLIT2
4p15.2
Slit2 plays a vital role in axon guidance by signaling through Robo receptors (ROBOs), like ROBO1.
Slit2 has been shown to inhibit leukocyte chemotaxis.
SLIT2 protein is a putative ligand for the ROBO receptors.
SLIT2 is frequently inactivated by promoter region hypermethylation and allele loss in pulmonary carcinomas and mammary carcinomas (#12384551#)
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