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MET

MIM.164860 7q31

MET protooncogene, HGFR, RCCP2, hepatocyte growth factor/scatter factor (HGF/SF) receptor

 

Pathology

-  germline mutations in familial papillary renal carcinoma (MIM.605074)
-  somatic mutations in sporadic papillary renal carcinoma (MIM.605074)
-  somatic mutations in childhood type hepatocellular carcinoma (MIM.114550)

References

-  Corso S, Comoglio PM, Giordano S. Cancer therapy: can the challenge be MET? Trends Mol Med. 2005 Jun;11(6):284-92. PMID: #15949770#

-  Dharmawardana PG, Giubellino A, Bottaro DP. Hereditary papillary renal carcinoma type I. Curr Mol Med. 2004 Dec;4(8):855-68. PMID: #15579033#

-  Rosario M, Birchmeier W. How to make tubes: signaling by the Met receptor tyrosine kinase. Trends Cell Biol. 2003 Jun;13(6):328-35. PMID: #12791299#



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