CDKN1B
MIM.600778 12p13
p27KIP1, KIP1, p27
p21 (CDKN1A) and p27 (CDKN1B) block the cell cycle by binding to cyclin-CDK complexes. p21 (CDKN1A) is induced by the tumor suppressor p53. p27 (CDKN1B) responds to growth suppressors such as transforming growth factor-? (TGFBs).
12p13 LOH in acute lymphoblastic leukemia
See also
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