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Tourette syndrome

Gilles de la Tourette syndrome

 

Gilles de la Tourette syndrome (GTS) is characterized by multiple motor and phonic tics and high comorbidity rates with other neurobehavioral disorders. It is hypothesized that frontal-subcortical pathways and a complex genetic background are involved in the etiopathogenesis of the disorder.

Susceptibility

-  germline mutations of SLITRK1 at 17q25



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