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nonspecific reactive hepatitis

 

Microscopical synopsis:

-  portal infiltration by mononuclear cells (mainly lymphocytes)
-  steatosis
-  focal hepatocyte necrosis
-  lobular inflammation
-  enlarged Kupffer's cells
-  Kupffer's cells hyperplasia
-  small lobular granulomatoid clusters
-  lobular macrophages aggregates
-  lobular lymphocytes aggregates

Etiology:

-  infections, sepsis
-  inflammatory diseases
-  gastrointestinal diseases
-  pancreatic diseases

Differential diagnosis:

-  resolving acute hepatitis
-  mild chronic persistent hepatis
-  chronic lobular hepatitis



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