ductular reaction

Definition: Increase in the number and prominence of small biliary channels in and around the portal tracts.

Synopsis:

tubular to elongated profiles
lined by cuboidal or columnar epithelium
well-defined lumen or not

Etiology:

acute or chronic cholestasis
sepsis
massive hepatic necrosis
hepatic fibrosis
hepatic cirrhosis
miscellaneous

Elementary lesions associated:

bile plugs
ductular dilatation
neutrophilic infiltration

Differential diagnosis:

must be distinguished from interlobular bile ducts

Ductular proliferation in biliary Langerhans histiocytosis

Ductular proliferation in Ellis-van Creveld disease

Ductular proliferation after massive heaptic necrosis - Fulminant auto-immune hapatitis

Ductular proliferation after massive hepatic necrosis - Fulminant auto-immune hapatitis

Ductular proliferation in nephronophthisis-associated hepatic disease

Ductular proliferation after massive hepatic necrosis - Fulminant auto-immune hepatitis

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