220-kD multiprotein complex from human platelets that induces actin polymerization at the L. monocytogenes cell surface and mediates bacterial motility.

This complex contains actin-related proteins (Arps) in the Arp2 and Arp3 families and therefore was named the Arp2/3 complex.

Subunits

Function

 The ARP2/3 complex promotes actin assembly in lamellipodia and may participate in lamellipodial protrusion.

Features

 actin assembly
 actin polymerization
 lamellipodia protrusion and retraction