Locus SGBS1 at Xq26 (MIM.312870)
mutation in the gene for glypican-3 (GPC3) in Simpson-Golabi-Behmel syndrome (MIM.312870)
Glypican-3 (GPC3) is a histological and serological marker of HCC.
Expression in tumors
melanoma (#15475451#)
See also
glypicans (GPCs)
References
Nakatsura T, Kageshita T, Ito S, Wakamatsu K, Monji M, Ikuta Y, Senju S, Ono T, Nishimura Y. Identification of glypican-3 as a novel tumor marker for melanoma. Clin Cancer Res. 2004 Oct 1;10(19):6612-21. PMID: #15475451#