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GPC3

MIM.300037 Xq26

 

Locus SGBS1 at Xq26 (MIM.312870)

Pathology

-  mutation in the gene for glypican-3 (GPC3) in Simpson-Golabi-Behmel syndrome (MIM.312870)

-  Glypican-3 (GPC3) is a histological and serological marker of HCC.

Expression in tumors

-  melanoma (#15475451#)

See also

-  glypicans (GPCs)

References

-  Nakatsura T, Kageshita T, Ito S, Wakamatsu K, Monji M, Ikuta Y, Senju S, Ono T, Nishimura Y. Identification of glypican-3 as a novel tumor marker for melanoma. Clin Cancer Res. 2004 Oct 1;10(19):6612-21. PMID: #15475451#



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