Focal adhesion kinase (FAK) have an important receptor-proximal position in the regulation of growth factor and integrin-stimulated cell motility.

Features

 FAK activation
 connections of FAK to focal contact formation
 FAK turnover
 FAK in cell invasion
 FAK in cell motility

References

 Schlaepfer DD, Mitra SK. Multiple connections link FAK to cell motility and invasion. Curr Opin Genet Dev. 2004 Feb;14(1):92-101. PMID: #15108811#